Metastatic breast cancer is a very heterogeneous disease, both from a clinical and a biological point of view.Despite being still incurable, the expanding therapeutic repertoire has determined a progressive increase in median survival.We describe the clinical Suitcases course of a 67-year-old woman with a locally advanced, hormone-receptor positive
Enhanced Secure Trusted AODV (ESTA) Protocol to Mitigate Blackhole Attack in Mobile Ad Hoc Networks
The self-organizing nature of the Mobile Ad hoc Networks (MANETs) provide a communication channel anywhere, anytime without any pre-existing network infrastructure.However, it is exposed to various vulnerabilities that may be exploited by the malicious Little Girls Woven Shirts nodes.One such malicious behavior is introduced by blackhole nodes, whi
Behavioural Analysis of Criminal Law: A Survey
This article is a survey of behavioural analysis of criminal law.Behavioural analysis of criminal law exploits Dresses social science methodologies (behavioural economics, psychology and even sociology) to explore the effects of criminal law norms and enforcement policy on criminals, judges, juries, lawyers and other decision-makers, to determine t
Subcellular drug targeting illuminates local kinase action
Deciphering how signaling enzymes operate within discrete microenvironments is fundamental to understanding biological processes.A-kinase Little Girls Woven Shirts anchoring proteins (AKAPs) restrict the range of action of protein kinases within intracellular compartments.We exploited the AKAP targeting concept to create genetically encoded platfor